Dry submicron particles are transported into the airways by means of airflow that is caused by inhalation, reaching from the sinuses in the upper airways to the bronchioli and alveoli in the lower airways.
When inhaled, the submicron salt particles travel through the throat and main tract down into the bronchi, bronchioli and alveoli as well as upper airways (sinuses). As soon as the dry submicron particles are deposited onto the lining inside the airways, 3 main mechanisms of action are executed.
- The dry particles absorb a maximum amount of humidity. This causes fluidization of which can improve the expectoration of mucus significantly.
- In addition, the dry particles can act as an active agent to decrease infection inside the airways.
- Dry submicron size salt particles could also act as an agent to stimulate the epithelium inside the airways to improve the transport of sputum out of the airways (mucociliary clearance).